#3528 DIALYSATE SODIUM: IS IT STILL MYTH OR NOT?
نویسندگان
چکیده
Abstract Background and Aims Pre-hemodialysis serum sodium levels can vary among patients, therefore, a single dialysate prescription may not be appropriate for all patients. The aim of the study was to investigate whether dialysis patients will have some beneficial effects different models sodium. Method 77 nondiabetic subjects performed 12 months hemodialysis (HD) sessions with concentration set up at 138 mmol/L, followed by additional 4 (each one lasted) wherein up: model 1: according pre-hemodialysis concentration, 2: in UF fluid, 3: profiling (144-136 every hour decreasing during dialysis), 4: stepwise (starting mmol/L reducing it week 1 next weeks). Blood pressure (BP), interdialytic weight gain (IDWG), thirst score, gradient were analysed. After standard hemodialyses, divided into normotensive, hypertensive hypotensive based on average systolic BP hemodialyses. Results Model resulted significantly lower (153.60±14.26 versus 133,61±11.88 mmHg; p = 0.000) IDWG (2.21±0.93 1.87±0.92 kg; 0.018) whereas normotensive showed only significant decrease (p 0,004). Hypertensive had highest compared other (p<0.05), increase 0,6% confirmed univariate regression analysis. Thirst score individualized-sodium HD no relationship between subjective feeling 0.368). influence 0.474 0.212, retrospectively). Patients who hypotensive, due frequent collapses unmeasurable blood values, as well ethical reasons, excluded from analysis this model. higher 3 groups 0.006) normo hipotensive 0.000), SBP DBP insignificant IDWG, but BP, score. Conclusion better clinical outcome sodium, didn't show any benefits.
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2023
ISSN: ['1460-2385', '0931-0509']
DOI: https://doi.org/10.1093/ndt/gfad063c_3528